منابع مشابه
Ion channels and vascular tone.
Ion channels in the plasma membrane of vascular muscle cells that form the walls of resistance arteries and arterioles play a central role in the regulation of vascular tone. Current evidence indicates that vascular smooth muscle cells express at least 4 different types of K(+) channels, 1 to 2 types of voltage-gated Ca(2+) channels, >/=2 types of Cl(-) channels, store-operated Ca(+) (SOC) chan...
متن کاملRole of potassium channels in regulation of cerebral vascular tone.
Several types of potassium (K+) channels are present in cerebral blood vessels. Opening or closure of these ion channels may have significant effects on membrane po tential, which is a major determinant of entry of extra cellular calcium and thus vascular tone, Because of the ionic properties of the cell membrane at rest, the change in activity of only a few K+ channels is sufficient to chang...
متن کاملIon channels and their functional role in vascular endothelium.
Endothelial cells (EC) form a unique signal-transducing surface in the vascular system. The abundance of ion channels in the plasma membrane of these nonexcitable cells has raised questions about their functional role. This review presents evidence for the involvement of ion channels in endothelial cell functions controlled by intracellular Ca(2+) signals, such as the production and release of ...
متن کاملO 13: Ion Channels in Autoimmune Neurodegeneration
Multiple sclerosis (MS) is a chronic inflammatory disease of the central nervous system characterized by widespread inflammation, focal demyelination and a variable degree of axonal and neuronal loss. Ionic conductances regulate T cell activation as well as neuronal function and thus have been found to play a crucial role in MS pathogenesis. Since present therapeutical approaches are only parti...
متن کاملTaurine and vascular tone modulation
Taurine, an ubiquitary amino acid in the organism, has important physiological functions like bile salt formation, neuronal excitability regulation, immunomodulation, electrolytes homeostasis preservation, osmoregulation, membrane stabilisation, apoptosis inhibition and cell protection. This review article is focusing on the complex vasoactive influence of the sulphur-amino acid and on the poss...
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ژورنال
عنوان ژورنال: Hypertension
سال: 2000
ISSN: 0194-911X,1524-4563
DOI: 10.1161/01.hyp.35.1.173